Striatal Neurons Expressing D(1) and D(2) Receptors are Morphologically Distinct and Differently Affected by Dopamine Denervation in Mice

The loss of nigrostriatal dopamine neurons in Parkinson’s disease induces a reduction in the number of dendritic spines on medium spiny neurons (MSNs) of the striatum expressing D(1) or D(2) dopamine receptor. Consequences on MSNs expressing both receptors (D(1)/D(2) MSNs) are currently unknown. We...

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Detalles Bibliográficos
Autores principales: Gagnon, D., Petryszyn, S., Sanchez, M. G., Bories, C., Beaulieu, J. M., De Koninck, Y., Parent, A., Parent, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269744/
https://www.ncbi.nlm.nih.gov/pubmed/28128287
http://dx.doi.org/10.1038/srep41432

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