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Do anti-amyloid beta protein antibody cross reactivities confound Alzheimer disease research?
BACKGROUND: Alzheimer disease (AD) research has focussed mainly on the amyloid beta protein (Aβ). However, many Aβ-and P3-type peptides derived from the amyloid precursor protein (APP) and peptides thought to derive from Aβ catabolism share sequence homology. Additionally, conformations can change d...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270220/ https://www.ncbi.nlm.nih.gov/pubmed/28126004 http://dx.doi.org/10.1186/s12952-017-0066-3 |