Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types

BACKGROUND: A healthy immune system requires immune cells that adapt rapidly to environmental challenges. This phenotypic plasticity can be mediated by transcriptional and epigenetic variability. RESULTS: We apply a novel analytical approach to measure and compare transcriptional and epigenetic vari...

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Detalles Bibliográficos
Autores principales: Ecker, Simone, Chen, Lu, Pancaldi, Vera, Bagger, Frederik O., Fernández, José María, Carrillo de Santa Pau, Enrique, Juan, David, Mann, Alice L., Watt, Stephen, Casale, Francesco Paolo, Sidiropoulos, Nikos, Rapin, Nicolas, Merkel, Angelika, Stunnenberg, Hendrik G., Stegle, Oliver, Frontini, Mattia, Downes, Kate, Pastinen, Tomi, Kuijpers, Taco W., Rico, Daniel, Valencia, Alfonso, Beck, Stephan, Soranzo, Nicole, Paul, Dirk S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270224/
https://www.ncbi.nlm.nih.gov/pubmed/28126036
http://dx.doi.org/10.1186/s13059-017-1156-8

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