De novo and rare mutations in the HSPA1L heat shock gene associated with inflammatory bowel disease

BACKGROUND: Inflammatory bowel disease (IBD) is a chronic, relapsing inflammatory disease of the gastrointestinal tract which includes ulcerative colitis and Crohn's disease. Genetic risk factors for IBD are not well understood. METHODS: We performed a family-based whole exome sequencing (WES)...

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Detalles Bibliográficos
Autores principales: Takahashi, Shinichi, Andreoletti, Gaia, Chen, Rui, Munehira, Yoichi, Batra, Akshay, Afzal, Nadeem A., Beattie, R. Mark, Bernstein, Jonathan A., Ennis, Sarah, Snyder, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270254/
https://www.ncbi.nlm.nih.gov/pubmed/28126021
http://dx.doi.org/10.1186/s13073-016-0394-9

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