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MOBAS: identification of disease-associated protein subnetworks using modularity-based scoring
Network-based analyses are commonly used as powerful tools to interpret the findings of genome-wide association studies (GWAS) in a functional context. In particular, identification of disease-associated functional modules, i.e., highly connected protein-protein interaction (PPI) subnetworks with hi...
Autores principales: | Ayati, Marzieh, Erten, Sinan, Chance, Mark R., Koyutürk, Mehmet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270451/ https://www.ncbi.nlm.nih.gov/pubmed/28194175 http://dx.doi.org/10.1186/s13637-015-0025-6 |
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