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Altered stoichiometry and nuclear delocalization of NonO and PSF promote cellular senescence

While cellular senescence is a critical mechanism to prevent malignant transformation of potentially mutated cells, persistence of senescent cells can also promote cancer and aging phenotypes. NonO/p54nrb and PSF are multifunctional hnRNPs typically found as a complex exclusively within the nuclei o...

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Detalles Bibliográficos
Autores principales:	Huang, Ching-Jung, Das, Utsab, Xie, Weijun, Ducasse, Miryam, Tucker, Haley O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270673/ https://www.ncbi.nlm.nih.gov/pubmed/27992859 http://dx.doi.org/10.18632/aging.101125

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