Altered S-nitrosylation of p53 is responsible for impaired antioxidant response in skeletal muscle during aging

p53 transcriptional activity has been proposed to regulate both homeostasis and sarcopenia of skeletal muscle during aging. However, the exact molecular function of p53 remains to be clearly defined. We demonstrated a requirement of nuclear p53 S-nitrosylation in inducing a nitric oxide/PGC-1α-media...

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Detalles Bibliográficos
Autores principales: Baldelli, Sara, Ciriolo, Maria Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270679/
https://www.ncbi.nlm.nih.gov/pubmed/28025407
http://dx.doi.org/10.18632/aging.101139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270679/
https://www.ncbi.nlm.nih.gov/pubmed/28025407
http://dx.doi.org/10.18632/aging.101139

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