TFEB ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin

Doxorubicin, a commonly used chemotherapy agent, induces severe cardio- and neurotoxicity. Molecular mechanisms of cardiotoxicity have been extensively studied, but mechanisms by which doxorubicin exhibits its neurotoxic properties remain unclear. Here, we show that doxorubicin impairs neuronal auto...

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Detalles Bibliográficos
Autores principales: Moruno Manchon, Jose Felix, Uzor, Ndidi-Ese, Kesler, Shelli R., Wefel, Jeffrey S., Townley, Debra M., Nagaraja, Archana Sidalaghatta, Pradeep, Sunila, Mangala, Lingegowda S., Sood, Anil K., Tsvetkov, Andrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270683/
https://www.ncbi.nlm.nih.gov/pubmed/27992857
http://dx.doi.org/10.18632/aging.101144

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