Integration of monolithic porous polymer with droplet-based microfluidics on a chip for nano/picoliter volume sample analysis

In this paper, a porous polymer nanostructure has been integrated with droplet-based microfluidics in a single planar format. Monolithic porous polymer (MPP) was formed selectively within a microfluidic channel. The resulting analyte bands were sequentially comartmentalised into droplets. This devic...

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Detalles Bibliográficos
Autores principales: Kim, Jin-young, Chang, Soo-Ik, deMello, Andrew J, O’Hare, Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Nano Technology Research Society 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271139/
https://www.ncbi.nlm.nih.gov/pubmed/28191388
http://dx.doi.org/10.1186/s40580-014-0003-9
Descripción
Sumario:In this paper, a porous polymer nanostructure has been integrated with droplet-based microfluidics in a single planar format. Monolithic porous polymer (MPP) was formed selectively within a microfluidic channel. The resulting analyte bands were sequentially comartmentalised into droplets. This device reduces band broadening and the effects of post-column dead volume by the combination of the two techniques. Moreover it offers the precise control of nano/picoliter volume samples.

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