Integration of monolithic porous polymer with droplet-based microfluidics on a chip for nano/picoliter volume sample analysis

In this paper, a porous polymer nanostructure has been integrated with droplet-based microfluidics in a single planar format. Monolithic porous polymer (MPP) was formed selectively within a microfluidic channel. The resulting analyte bands were sequentially comartmentalised into droplets. This devic...

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Detalles Bibliográficos
Autores principales: Kim, Jin-young, Chang, Soo-Ik, deMello, Andrew J, O’Hare, Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Nano Technology Research Society 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271139/
https://www.ncbi.nlm.nih.gov/pubmed/28191388
http://dx.doi.org/10.1186/s40580-014-0003-9
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author Kim, Jin-young
Chang, Soo-Ik
deMello, Andrew J
O’Hare, Danny
author_facet Kim, Jin-young
Chang, Soo-Ik
deMello, Andrew J
O’Hare, Danny
author_sort Kim, Jin-young
collection PubMed
description In this paper, a porous polymer nanostructure has been integrated with droplet-based microfluidics in a single planar format. Monolithic porous polymer (MPP) was formed selectively within a microfluidic channel. The resulting analyte bands were sequentially comartmentalised into droplets. This device reduces band broadening and the effects of post-column dead volume by the combination of the two techniques. Moreover it offers the precise control of nano/picoliter volume samples.
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spelling pubmed-52711392017-02-09 Integration of monolithic porous polymer with droplet-based microfluidics on a chip for nano/picoliter volume sample analysis Kim, Jin-young Chang, Soo-Ik deMello, Andrew J O’Hare, Danny Nano Converg Research In this paper, a porous polymer nanostructure has been integrated with droplet-based microfluidics in a single planar format. Monolithic porous polymer (MPP) was formed selectively within a microfluidic channel. The resulting analyte bands were sequentially comartmentalised into droplets. This device reduces band broadening and the effects of post-column dead volume by the combination of the two techniques. Moreover it offers the precise control of nano/picoliter volume samples. Korea Nano Technology Research Society 2014-03-28 2014 /pmc/articles/PMC5271139/ /pubmed/28191388 http://dx.doi.org/10.1186/s40580-014-0003-9 Text en © Kim et al.; licensee Springer 2014 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Kim, Jin-young
Chang, Soo-Ik
deMello, Andrew J
O’Hare, Danny
Integration of monolithic porous polymer with droplet-based microfluidics on a chip for nano/picoliter volume sample analysis
title Integration of monolithic porous polymer with droplet-based microfluidics on a chip for nano/picoliter volume sample analysis
title_full Integration of monolithic porous polymer with droplet-based microfluidics on a chip for nano/picoliter volume sample analysis
title_fullStr Integration of monolithic porous polymer with droplet-based microfluidics on a chip for nano/picoliter volume sample analysis
title_full_unstemmed Integration of monolithic porous polymer with droplet-based microfluidics on a chip for nano/picoliter volume sample analysis
title_short Integration of monolithic porous polymer with droplet-based microfluidics on a chip for nano/picoliter volume sample analysis
title_sort integration of monolithic porous polymer with droplet-based microfluidics on a chip for nano/picoliter volume sample analysis
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271139/
https://www.ncbi.nlm.nih.gov/pubmed/28191388
http://dx.doi.org/10.1186/s40580-014-0003-9
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