A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate

Sunitinib is a tyrosine kinase inhibitor approved for the treatment of multiple solid tumors. However, cardiotoxicity is of increasing concern, with a need to develop rational mechanism driven approaches for the early detection of cardiac dysfunction. We sought to interrogate changes in cardiac ener...

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Detalles Bibliográficos
Autores principales: O’Farrell, Alice C., Evans, Rhys, Silvola, Johanna M. U., Miller, Ian S., Conroy, Emer, Hector, Suzanne, Cary, Maurice, Murray, David W., Jarzabek, Monika A., Maratha, Ashwini, Alamanou, Marina, Udupi, Girish Mallya, Shiels, Liam, Pallaud, Celine, Saraste, Antti, Liljenbäck, Heidi, Jauhiainen, Matti, Oikonen, Vesa, Ducret, Axel, Cutler, Paul, McAuliffe, Fionnuala M., Rousseau, Jacques A., Lecomte, Roger, Gascon, Suzanne, Arany, Zoltan, Ky, Bonnie, Force, Thomas, Knuuti, Juhani, Gallagher, William M., Roivainen, Anne, Byrne, Annette T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271313/
https://www.ncbi.nlm.nih.gov/pubmed/28129334
http://dx.doi.org/10.1371/journal.pone.0169964

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