Prolonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cells

AIMS: Pancreatic β-cells synthesize and release serotonin (5 hydroxytryptamine, 5HT); however, the role of 5HT receptors on glucose stimulated insulin secretion (GSIS) and the mechanisms mediating this function is not fully understood. The aims of this study were to determine the expression profile...

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Detalles Bibliográficos
Autores principales: Cataldo, Luis Rodrigo, Mizgier, María L., Bravo Sagua, Roberto, Jaña, Fabián, Cárdenas, César, Llanos, Paola, Busso, Dolores, Olmos, Pablo, Galgani, José E., Santos, José L., Cortés, Víctor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271329/
https://www.ncbi.nlm.nih.gov/pubmed/28129327
http://dx.doi.org/10.1371/journal.pone.0170213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271329/
https://www.ncbi.nlm.nih.gov/pubmed/28129327
http://dx.doi.org/10.1371/journal.pone.0170213

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