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Prolonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cells
AIMS: Pancreatic β-cells synthesize and release serotonin (5 hydroxytryptamine, 5HT); however, the role of 5HT receptors on glucose stimulated insulin secretion (GSIS) and the mechanisms mediating this function is not fully understood. The aims of this study were to determine the expression profile...
Autores principales: | Cataldo, Luis Rodrigo, Mizgier, María L., Bravo Sagua, Roberto, Jaña, Fabián, Cárdenas, César, Llanos, Paola, Busso, Dolores, Olmos, Pablo, Galgani, José E., Santos, José L., Cortés, Víctor A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271329/ https://www.ncbi.nlm.nih.gov/pubmed/28129327 http://dx.doi.org/10.1371/journal.pone.0170213 |
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