Leishmania HASP and SHERP Genes Are Required for In Vivo Differentiation, Parasite Transmission and Virulence Attenuation in the Host

Differentiation of extracellular Leishmania promastigotes within their sand fly vector, termed metacyclogenesis, is considered to be essential for parasites to regain mammalian host infectivity. Metacyclogenesis is accompanied by changes in the local parasite environment, including secretion of comp...

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Detalles Bibliográficos
Autores principales: Doehl, Johannes S. P., Sádlová, Jovana, Aslan, Hamide, Pružinová, Kateřina, Metangmo, Sonia, Votýpka, Jan, Kamhawi, Shaden, Volf, Petr, Smith, Deborah F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271408/
https://www.ncbi.nlm.nih.gov/pubmed/28095465
http://dx.doi.org/10.1371/journal.ppat.1006130

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