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Novel Phospho-Tau Monoclonal Antibody Generated Using a Liposomal Vaccine, with Enhanced Recognition of a Conformational Tauopathy Epitope

The microtubule-associated protein Tau is an intrinsically unfolded, very soluble neuronal protein. Under still unknown circumstances, Tau protein forms soluble oligomers and insoluble aggregates that are closely linked to the cause and progression of various brain pathologies, including Alzheimer’s...

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Detalles Bibliográficos
Autores principales:	Theunis, Clara, Adolfsson, Oskar, Crespo-Biel, Natalia, Piorkowska, Kasia, Pihlgren, Maria, Hickman, David T., Gafner, Valérie, Borghgraef, Peter, Devijver, Herman, Pfeifer, Andrea, Van Leuven, Fred, Muhs, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271481/ https://www.ncbi.nlm.nih.gov/pubmed/28035925 http://dx.doi.org/10.3233/JAD-160695

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