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Therapeutic Potential of Tricyclo-DNA antisense oligonucleotides
Oligonucleotide therapeutics hold great promise for the treatment of various diseases and the antisense field is constantly gaining interest due to the development of more potent and nuclease resistant chemistries. Despite a rather low success rate with only three antisense drugs being clinically ap...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271482/ https://www.ncbi.nlm.nih.gov/pubmed/27854216 http://dx.doi.org/10.3233/JND-160146 |