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“Get the Balance Right”: Pathological Significance of Autophagy Perturbation in Neuromuscular Disorders

Recent research has revealed that autophagy, a major catabolic process in cells, is dysregulated in several neuromuscular diseases and contributes to the muscle wasting caused by non-muscle disorders (e.g. cancer cachexia) or during aging (i.e. sarcopenia). From there, the idea arose to interfere wi...

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Detalles Bibliográficos
Autores principales: Castets, Perrine, Frank, Stephan, Sinnreich, Michael, Rüegg, Markus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271579/
https://www.ncbi.nlm.nih.gov/pubmed/27854220
http://dx.doi.org/10.3233/JND-160153

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