Cross-talks via mTORC2 can explain enhanced activation in response to insulin in diabetic patients

The molecular mechanisms of insulin resistance in Type 2 diabetes have been extensively studied in primary human adipocytes, and mathematical modelling has clarified the central role of attenuation of mammalian target of rapamycin (mTOR) complex 1 (mTORC1) activity in the diabetic state. Attenuation...

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Detalles Bibliográficos
Autores principales: Magnusson, Rasmus, Gustafsson, Mika, Cedersund, Gunnar, Strålfors, Peter, Nyman, Elin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271673/
https://www.ncbi.nlm.nih.gov/pubmed/27986865
http://dx.doi.org/10.1042/BSR20160514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271673/
https://www.ncbi.nlm.nih.gov/pubmed/27986865
http://dx.doi.org/10.1042/BSR20160514

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