CDC42-interacting protein 4 promotes metastasis of nasopharyngeal carcinoma by mediating invadopodia formation and activating EGFR signaling

BACKGROUND: Nasopharyngeal carcinoma (NPC) is a common malignancy in Southern China and Southeast Asia. In this study, we investigated the functional and molecular mechanisms by which CDC42-interacting protein 4 (CIP4) influences NPC. METHODS: The expression levels of CIP4 were examined by Western b...

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Detalles Bibliográficos
Autores principales: Meng, Dong-Fang, Xie, Ping, Peng, Li-Xia, Sun, Rui, Luo, Dong-Hua, Chen, Qiu-Yan, Lv, Xing, Wang, Lin, Chen, Ming-Yuan, Mai, Hai-Qiang, Guo, Ling, Guo, Xiang, Zheng, Li-Sheng, Cao, Li, Yang, Jun-Ping, Wang, Meng-Yao, Mei, Yan, Qiang, Yuan-Yuan, Zhang, Zi-Meng, Yun, Jing-Ping, Huang, Bi-Jun, Qian, Chao-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5273811/
https://www.ncbi.nlm.nih.gov/pubmed/28129778
http://dx.doi.org/10.1186/s13046-016-0483-z

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