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Establishment of a rat model with diet-induced coronary atherosclerosis

Coronary atherosclerotic disease is a serious disease in humans, but no suitable animal model is available currently for further studies. We used apolipoprotein E gene knockout (ApoE KO) rats to induce hypercholesterolemia through a special high cholesterol/bile salt diet (Paigen diet), then analyze...

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Detalles Bibliográficos
Autores principales:	Gao, Mingming, Xin, Guo, Qiu, Xu, Wang, Yuhui, Liu, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5274512/ https://www.ncbi.nlm.nih.gov/pubmed/28808185 http://dx.doi.org/10.7555/JBR.31.20160020

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