An independent, landmark-dominated head direction signal in dysgranular retrosplenial cortex

We investigated how landmarks influence the brain’s computation of head direction and found that in a bi-directionally symmetrical environment, some neurons in dysgranular retrosplenial cortex showed bi-directional firing patterns. This indicates dominance of neural activity by local environmental c...

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Autores principales: Jacob, Pierre-Yves, Casali, Giulio, Spieser, Laure, Page, Hector, Overington, Dorothy, Jeffery, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5274535/
https://www.ncbi.nlm.nih.gov/pubmed/27991898
http://dx.doi.org/10.1038/nn.4465
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author Jacob, Pierre-Yves
Casali, Giulio
Spieser, Laure
Page, Hector
Overington, Dorothy
Jeffery, Kate
author_facet Jacob, Pierre-Yves
Casali, Giulio
Spieser, Laure
Page, Hector
Overington, Dorothy
Jeffery, Kate
author_sort Jacob, Pierre-Yves
collection PubMed
description We investigated how landmarks influence the brain’s computation of head direction and found that in a bi-directionally symmetrical environment, some neurons in dysgranular retrosplenial cortex showed bi-directional firing patterns. This indicates dominance of neural activity by local environmental cues even when these conflict with the global head direction signal. It suggests a mechanism for associating landmarks to or dissociating them from the head direction signal, according to their directional stability/utility.
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spelling pubmed-52745352017-06-19 An independent, landmark-dominated head direction signal in dysgranular retrosplenial cortex Jacob, Pierre-Yves Casali, Giulio Spieser, Laure Page, Hector Overington, Dorothy Jeffery, Kate Nat Neurosci Article We investigated how landmarks influence the brain’s computation of head direction and found that in a bi-directionally symmetrical environment, some neurons in dysgranular retrosplenial cortex showed bi-directional firing patterns. This indicates dominance of neural activity by local environmental cues even when these conflict with the global head direction signal. It suggests a mechanism for associating landmarks to or dissociating them from the head direction signal, according to their directional stability/utility. 2016-12-19 2017-02 /pmc/articles/PMC5274535/ /pubmed/27991898 http://dx.doi.org/10.1038/nn.4465 Text en Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Jacob, Pierre-Yves
Casali, Giulio
Spieser, Laure
Page, Hector
Overington, Dorothy
Jeffery, Kate
An independent, landmark-dominated head direction signal in dysgranular retrosplenial cortex
title An independent, landmark-dominated head direction signal in dysgranular retrosplenial cortex
title_full An independent, landmark-dominated head direction signal in dysgranular retrosplenial cortex
title_fullStr An independent, landmark-dominated head direction signal in dysgranular retrosplenial cortex
title_full_unstemmed An independent, landmark-dominated head direction signal in dysgranular retrosplenial cortex
title_short An independent, landmark-dominated head direction signal in dysgranular retrosplenial cortex
title_sort independent, landmark-dominated head direction signal in dysgranular retrosplenial cortex
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5274535/
https://www.ncbi.nlm.nih.gov/pubmed/27991898
http://dx.doi.org/10.1038/nn.4465
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