Cargando…

Tracking Monocyte Recruitment and Macrophage Accumulation in Atherosclerotic Plaque Progression Using a Novel hCD68GFP/ApoE(−/−) Reporter Mouse—Brief Report

OBJECTIVE—: To create a model of atherosclerosis using green fluorescent protein (GFP)–targeted monocytes/macrophages, allowing analysis of both endogenous GFP(+) and adoptively transferred GFP(+) myeloid cells in arterial inflammation. APPROACH AND RESULTS—: hCD68GFP reporter mice were crossed with...

Descripción completa

Detalles Bibliográficos
Autores principales: McNeill, Eileen, Iqbal, Asif J., Jones, Daniel, Patel, Jyoti, Coutinho, Patricia, Taylor, Lewis, Greaves, David R., Channon, Keith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5274540/
https://www.ncbi.nlm.nih.gov/pubmed/27908893
http://dx.doi.org/10.1161/ATVBAHA.116.308367

Ejemplares similares