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Alpha-Ketoglutarate as a Molecule with Pleiotropic Activity: Well-Known and Novel Possibilities of Therapeutic Use

Alpha-ketoglutarate (AKG), an endogenous intermediary metabolite in the Krebs cycle, is a molecule involved in multiple metabolic and cellular pathways. It functions as an energy donor, a precursor in the amino acid biosynthesis, a signalling molecule, as well as a regulator of epigenetic processes...

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Detalles Bibliográficos
Autores principales: Zdzisińska, Barbara, Żurek, Aleksandra, Kandefer-Szerszeń, Martyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5274648/
https://www.ncbi.nlm.nih.gov/pubmed/27326424
http://dx.doi.org/10.1007/s00005-016-0406-x