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Evaluation of an Albumin-Binding Domain Protein Fused to Recombinant Human IL-2 and Its Effects on the Bioactivity and Serum Half-Life of the Cytokine

BACKGROUND: Cancer immunotherapy is a promising strategy for cancer treatment. In this strategy, the immune system is triggered to destroy cancer cells. IL-2 is an important factor in passive cancer immunotherapy that helps modulating some important immune functions. One of the IL-2 limitations is l...

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Detalles Bibliográficos
Autores principales: Adabi, Elham, Saebi, Fateme, Hasan-Abad, Amin Moradi, Teimoori-Toolabi, Ladan, Kardar, Gholam Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5274714/
https://www.ncbi.nlm.nih.gov/pubmed/27805072
http://dx.doi.org/10.18869/acadpub.ibj.21.2.77