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Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance
Serine hydrolases are a large family of multifunctional enzymes known to influence obesity. Here, we performed activity-based protein profiling to assess the functional level of serine hydrolases in liver biopsies from lean and obese humans in order to gain mechanistic insight into the pathophysiolo...
Autores principales: | Ruby, Maxwell A., Massart, Julie, Hunerdosse, Devon M., Schönke, Milena, Correia, Jorge C., Louie, Sharon M., Ruas, Jorge L., Näslund, Erik, Nomura, Daniel K., Zierath, Juleen R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5276805/ https://www.ncbi.nlm.nih.gov/pubmed/28099843 http://dx.doi.org/10.1016/j.celrep.2016.12.070 |
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