Celecoxib and 2,5‐dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β‐catenin signaling pathway

We previously reported that celecoxib, a selective COX‐2 inhibitor, strongly inhibited human colon cancer cell proliferation by suppressing the Wnt/β‐catenin signaling pathway. 2,5‐Dimethylcelecoxib (DM‐celecoxib), a celecoxib analog that does not inhibit COX‐2, has also been reported to have an ant...

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Detalles Bibliográficos
Autores principales: Egashira, Issei, Takahashi‐Yanaga, Fumi, Nishida, Risa, Arioka, Masaki, Igawa, Kazunobu, Tomooka, Katsuhiko, Nakatsu, Yoshimichi, Tsuzuki, Teruhisa, Nakabeppu, Yusaku, Kitazono, Takanari, Sasaguri, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5276826/
https://www.ncbi.nlm.nih.gov/pubmed/27761963
http://dx.doi.org/10.1111/cas.13106

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