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Modulation of Replicative Lifespan in Cryptococcus neoformans: Implications for Virulence

The fungal pathogen, Cryptococcus neoformans, has been shown to undergo replicative aging. Old cells are characterized by advanced generational age and phenotypic changes that appear to mediate enhanced resistance to host and antifungal-based killing. As a consequence of this age-associated resilien...

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Detalles Bibliográficos
Autores principales: Bouklas, Tejas, Jain, Neena, Fries, Bettina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5276861/
https://www.ncbi.nlm.nih.gov/pubmed/28194146
http://dx.doi.org/10.3389/fmicb.2017.00098