Suppression of Excessive Histone Deacetylases Activity in Diabetic Hearts Attenuates Myocardial Ischemia/Reperfusion Injury via Mitochondria Apoptosis Pathway

Background. Histone deacetylases (HDACs) play a pivotal role in signaling modification and gene transcriptional regulation that are essential for cardiovascular pathophysiology. Diabetic hearts with higher HDACs activity were more vulnerable to myocardial ischemia/reperfusion (MI/R) injury compared...

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Detalles Bibliográficos
Autores principales: Wu, Yang, Leng, Yan, Meng, Qingtao, Xue, Rui, Zhao, Bo, Zhan, Liying, Xia, Zhongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278197/
https://www.ncbi.nlm.nih.gov/pubmed/28191472
http://dx.doi.org/10.1155/2017/8208065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278197/
https://www.ncbi.nlm.nih.gov/pubmed/28191472
http://dx.doi.org/10.1155/2017/8208065

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