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RNA-Binding Protein Dnd1 Promotes Breast Cancer Apoptosis by Stabilizing the Bim mRNA in a miR-221 Binding Site

RNA-binding proteins (RBPs) and miRNAs are capable of controlling processes in normal development and cancer. Both of them could determine RNA transcripts fate from synthesis to decay. One such RBP, Dead end (Dnd1), is essential for regulating germ-cell viability and suppresses the germ-cell tumors...

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Detalles Bibliográficos
Autores principales: Cheng, Feng, Pan, Ying, Lu, Yi-Min, Zhu, Lei, Chen, Shuzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278209/
https://www.ncbi.nlm.nih.gov/pubmed/28191469
http://dx.doi.org/10.1155/2017/9596152

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