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Estimated reductions in cardiovascular and gastric cancer disease burden through salt policies in England: an IMPACT(NCD) microsimulation study

OBJECTIVE: To estimate the impact and equity of existing and potential UK salt reduction policies on primary prevention of cardiovascular disease (CVD) and gastric cancer (GCa) in England. DESIGN: A microsimulation study of a close-to-reality synthetic population. In the first period, 2003–2015, we...

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Autores principales: Kypridemos, Chris, Guzman-Castillo, Maria, Hyseni, Lirije, Hickey, Graeme L, Bandosz, Piotr, Buchan, Iain, Capewell, Simon, O'Flaherty, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278253/
https://www.ncbi.nlm.nih.gov/pubmed/28119387
http://dx.doi.org/10.1136/bmjopen-2016-013791
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author Kypridemos, Chris
Guzman-Castillo, Maria
Hyseni, Lirije
Hickey, Graeme L
Bandosz, Piotr
Buchan, Iain
Capewell, Simon
O'Flaherty, Martin
author_facet Kypridemos, Chris
Guzman-Castillo, Maria
Hyseni, Lirije
Hickey, Graeme L
Bandosz, Piotr
Buchan, Iain
Capewell, Simon
O'Flaherty, Martin
author_sort Kypridemos, Chris
collection PubMed
description OBJECTIVE: To estimate the impact and equity of existing and potential UK salt reduction policies on primary prevention of cardiovascular disease (CVD) and gastric cancer (GCa) in England. DESIGN: A microsimulation study of a close-to-reality synthetic population. In the first period, 2003–2015, we compared the impact of current policy against a counterfactual ‘no intervention’ scenario, which assumed salt consumption persisted at 2003 levels. For 2016–2030, we assumed additional legislative policies could achieve a steeper salt decline and we compared this against the counterfactual scenario that the downward trend in salt consumption observed between 2001 and 2011 would continue up to 2030. SETTING: Synthetic population with similar characteristics to the non-institutionalised population of England. PARTICIPANTS: Synthetic individuals with traits informed by the Health Survey for England. MAIN MEASURE: CVD and GCa cases and deaths prevented or postponed, stratified by fifths of socioeconomic status using the Index of Multiple Deprivation. RESULTS: Since 2003, current salt policies have prevented or postponed ∼52 000 CVD cases (IQR: 34 000–76 000) and 10 000 CVD deaths (IQR: 3000–17 000). In addition, the current policies have prevented ∼5000 new cases of GCa (IQR: 2000–7000) resulting in about 2000 fewer deaths (IQR: 0–4000). This policy did not reduce socioeconomic inequalities in CVD, and likely increased inequalities in GCa. Additional legislative policies from 2016 could further prevent or postpone ∼19 000 CVD cases (IQR: 8000–30 000) and 3600 deaths by 2030 (IQR: −400–8100) and may reduce inequalities. Similarly for GCa, 1200 cases (IQR: −200–3000) and 700 deaths (IQR: −900–2300) could be prevented or postponed with a neutral impact on inequalities. CONCLUSIONS: Current salt reduction policies are powerfully effective in reducing the CVD and GCa burdens overall but fail to reduce the inequalities involved. Additional structural policies could achieve further, more equitable health benefits.
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spelling pubmed-52782532017-02-07 Estimated reductions in cardiovascular and gastric cancer disease burden through salt policies in England: an IMPACT(NCD) microsimulation study Kypridemos, Chris Guzman-Castillo, Maria Hyseni, Lirije Hickey, Graeme L Bandosz, Piotr Buchan, Iain Capewell, Simon O'Flaherty, Martin BMJ Open Public Health OBJECTIVE: To estimate the impact and equity of existing and potential UK salt reduction policies on primary prevention of cardiovascular disease (CVD) and gastric cancer (GCa) in England. DESIGN: A microsimulation study of a close-to-reality synthetic population. In the first period, 2003–2015, we compared the impact of current policy against a counterfactual ‘no intervention’ scenario, which assumed salt consumption persisted at 2003 levels. For 2016–2030, we assumed additional legislative policies could achieve a steeper salt decline and we compared this against the counterfactual scenario that the downward trend in salt consumption observed between 2001 and 2011 would continue up to 2030. SETTING: Synthetic population with similar characteristics to the non-institutionalised population of England. PARTICIPANTS: Synthetic individuals with traits informed by the Health Survey for England. MAIN MEASURE: CVD and GCa cases and deaths prevented or postponed, stratified by fifths of socioeconomic status using the Index of Multiple Deprivation. RESULTS: Since 2003, current salt policies have prevented or postponed ∼52 000 CVD cases (IQR: 34 000–76 000) and 10 000 CVD deaths (IQR: 3000–17 000). In addition, the current policies have prevented ∼5000 new cases of GCa (IQR: 2000–7000) resulting in about 2000 fewer deaths (IQR: 0–4000). This policy did not reduce socioeconomic inequalities in CVD, and likely increased inequalities in GCa. Additional legislative policies from 2016 could further prevent or postpone ∼19 000 CVD cases (IQR: 8000–30 000) and 3600 deaths by 2030 (IQR: −400–8100) and may reduce inequalities. Similarly for GCa, 1200 cases (IQR: −200–3000) and 700 deaths (IQR: −900–2300) could be prevented or postponed with a neutral impact on inequalities. CONCLUSIONS: Current salt reduction policies are powerfully effective in reducing the CVD and GCa burdens overall but fail to reduce the inequalities involved. Additional structural policies could achieve further, more equitable health benefits. BMJ Publishing Group 2017-01-24 /pmc/articles/PMC5278253/ /pubmed/28119387 http://dx.doi.org/10.1136/bmjopen-2016-013791 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
spellingShingle Public Health
Kypridemos, Chris
Guzman-Castillo, Maria
Hyseni, Lirije
Hickey, Graeme L
Bandosz, Piotr
Buchan, Iain
Capewell, Simon
O'Flaherty, Martin
Estimated reductions in cardiovascular and gastric cancer disease burden through salt policies in England: an IMPACT(NCD) microsimulation study
title Estimated reductions in cardiovascular and gastric cancer disease burden through salt policies in England: an IMPACT(NCD) microsimulation study
title_full Estimated reductions in cardiovascular and gastric cancer disease burden through salt policies in England: an IMPACT(NCD) microsimulation study
title_fullStr Estimated reductions in cardiovascular and gastric cancer disease burden through salt policies in England: an IMPACT(NCD) microsimulation study
title_full_unstemmed Estimated reductions in cardiovascular and gastric cancer disease burden through salt policies in England: an IMPACT(NCD) microsimulation study
title_short Estimated reductions in cardiovascular and gastric cancer disease burden through salt policies in England: an IMPACT(NCD) microsimulation study
title_sort estimated reductions in cardiovascular and gastric cancer disease burden through salt policies in england: an impact(ncd) microsimulation study
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278253/
https://www.ncbi.nlm.nih.gov/pubmed/28119387
http://dx.doi.org/10.1136/bmjopen-2016-013791
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