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REV-ERBα regulates Fgf21 expression in the liver via hepatic nuclear factor 6

The circadian clock contributes to the timing of many body functions including metabolism and reproduction. The hepatokine fibroblast growth factor 21 (FGF21) is a critical metabolic regulator involved in modulation of fertility. Here we show that lack of the clock component REV-ERBα elevates FGF21...

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Detalles Bibliográficos
Autores principales:	Chavan, Rohit, Preitner, Nadia, Okabe, Takashi, Strittmatter, Laureen Mansencal, Xu, Cheng, Ripperger, Jürgen A., Pitteloud, Nelly, Albrecht, Urs
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278426/ https://www.ncbi.nlm.nih.gov/pubmed/27875243 http://dx.doi.org/10.1242/bio.021519

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