Cardiomyocyte­-specific expression of the nuclear matrix protein, CIZ1, stimulates production of mono-nucleated cells with an extended window of proliferation in the postnatal mouse heart

Myocardial injury in mammals leads to heart failure through pathological cardiac remodelling that includes hypertrophy, fibrosis and ventricular dilatation. Central to this is inability of the mammalian cardiomyocyte to self-renew due to entering a quiescent state after birth. Modulation of the card...

Descripción completa

Detalles Bibliográficos
Autores principales: Bageghni, Sumia A., Frentzou, Georgia A., Drinkhill, Mark J., Mansfield, William, Coverley, Dawn, Ainscough, Justin F. X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278428/
https://www.ncbi.nlm.nih.gov/pubmed/27934662
http://dx.doi.org/10.1242/bio.021550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278428/
https://www.ncbi.nlm.nih.gov/pubmed/27934662
http://dx.doi.org/10.1242/bio.021550

Ejemplares similares