5-aminolevulinic acid combined with ferrous ion reduces adiposity and improves glucose tolerance in diet-induced obese mice via enhancing mitochondrial function

BACKGROUND: Mitochondrial dysfunction is associated with obesity and various obesity-associated pathological conditions including glucose intolerance. 5-Aminolevulinic acid (ALA), a precursor of heme metabolites, is a natural amino acid synthesized in the mitochondria, and various types of cytochrom...

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Detalles Bibliográficos
Autores principales: Ota, Urara, Hara, Takeshi, Nakagawa, Hitoshi, Tsuru, Emi, Tsuda, Masayuki, Kamiya, Atsuko, Kuroda, Yasushi, Kitajima, Yuya, Koda, Aya, Ishizuka, Masahiro, Fukuhara, Hideo, Inoue, Keiji, Shuin, Taro, Nakajima, Motowo, Tanaka, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278573/
https://www.ncbi.nlm.nih.gov/pubmed/28132645
http://dx.doi.org/10.1186/s40360-016-0108-3

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