Cargando…
Extra-nuclear effects of estrogen on cortical bone in males require ERαAF-1
Estradiol (E2) signaling via estrogen receptor alpha (ERα) is important for the male skeleton as demonstrated by ERα inactivation in both mice and man. ERα mediates estrogenic effects not only by translocating to the nucleus and affecting gene transcription but also by extra-nuclear actions e.g., tr...
Autores principales: | Farman, H H, Wu, J, Gustafsson, K L, Windahl, S H, Kim, S H, Katzenellenbogen, J A, Ohlsson, C, Lagerquist, M K |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278601/ https://www.ncbi.nlm.nih.gov/pubmed/28057769 http://dx.doi.org/10.1530/JME-16-0209 |
Ejemplares similares
-
Phosphorylation of S122 in ERα is important for the skeletal response to estrogen treatment in male mice
por: Horkeby, Karin, et al.
Publicado: (2022) -
ERα expression in T lymphocytes is dispensable for estrogenic effects in bone
por: Gustafsson, K L, et al.
Publicado: (2018) -
Female Mice Lacking Estrogen Receptor-α in Hypothalamic Proopiomelanocortin (POMC) Neurons Display Enhanced Estrogenic Response on Cortical Bone Mass
por: Farman, H. H., et al.
Publicado: (2016) -
The role of membrane ERα signaling in bone and other major estrogen responsive tissues
por: Gustafsson, K. L., et al.
Publicado: (2016) -
SERMs have substance-specific effects on bone, and these effects are mediated via ERαAF-1 in female mice
por: Börjesson, Anna E., et al.
Publicado: (2016)