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Phosphorylation of XIAP by CDK1–cyclin-B1 controls mitotic cell death
Regulation of cell death is crucial for the response of cancer cells to drug treatments that cause arrest in mitosis, and is likely to be important for protection against chromosome instability in normal cells. Prolonged mitotic arrest can result in cell death by activation of caspases and the induc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278668/ https://www.ncbi.nlm.nih.gov/pubmed/27927753 http://dx.doi.org/10.1242/jcs.192310 |