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Neuronal oxidative damage and dendritic degeneration following activation of CD14-dependent innate immune response in vivo
The cause-and-effect relationship between innate immune activation and neurodegeneration has been difficult to prove in complex animal models and patients. Here we review findings from a model of direct innate immune activation via CD14 stimulation using intracerebroventricular injection of lipopoly...
Autores principales: | Milatovic, Dejan, Zaja-Milatovic, Snjezana, Montine, Kathleen S, Shie, Feng-Shiun, Montine, Thomas J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC527876/ https://www.ncbi.nlm.nih.gov/pubmed/15498098 http://dx.doi.org/10.1186/1742-2094-1-20 |
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