Cargando…

Metabolomic signatures associated with disease severity in multiple sclerosis

OBJECTIVE: To identify differences in the metabolomic profile in the serum of patients with multiple sclerosis (MS) compared to controls and to identify biomarkers of disease severity. METHODS: We studied 2 cohorts of patients with MS: a retrospective longitudinal cohort of 238 patients and 74 contr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Villoslada, Pablo, Alonso, Cristina, Agirrezabal, Ion, Kotelnikova, Ekaterina, Zubizarreta, Irati, Pulido-Valdeolivas, Irene, Saiz, Albert, Comabella, Manuel, Montalban, Xavier, Villar, Luisa, Alvarez-Cermeño, Jose Carlos, Fernández, Oscar, Alvarez-Lafuente, Roberto, Arroyo, Rafael, Castro, Azucena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278923/ https://www.ncbi.nlm.nih.gov/pubmed/28180139 http://dx.doi.org/10.1212/NXI.0000000000000321

Ejemplares similares

Dynamics and heterogeneity of brain damage in multiple sclerosis
por: Kotelnikova, Ekaterina, et al.
Publicado: (2017)

Combined walking outcome measures identify clinically meaningful response to prolonged-release fampridine
por: Sola-Valls, Núria, et al.
Publicado: (2018)

Validation of semaphorin 7A and ala-β-his-dipeptidase as biomarkers associated with the conversion from clinically isolated syndrome to multiple sclerosis
por: Cantó, Ester, et al.
Publicado: (2014)

Predictors of vision impairment in Multiple Sclerosis
por: Sanchez-Dalmau, Bernardo, et al.
Publicado: (2018)

Knowledge Retrieval from PubMed Abstracts and Electronic Medical Records with the Multiple Sclerosis Ontology
por: Malhotra, Ashutosh, et al.
Publicado: (2015)

Circulating EZH2-positive T cells are decreased in multiple sclerosis patients
por: Malhotra, Sunny, et al.
Publicado: (2018)

Magnetic resonance markers of tissue damage related to connectivity disruption in multiple sclerosis
por: Solana, Elisabeth, et al.
Publicado: (2018)

Tolerogenic Dendritic Cells as a Promising Antigen-Specific Therapy in the Treatment of Multiple Sclerosis and Neuromyelitis Optica From Preclinical to Clinical Trials
por: Flórez-Grau, Georgina, et al.
Publicado: (2018)

Influence of the LILRA3 Deletion on Multiple Sclerosis Risk: Original Data and Meta-Analysis
por: Ortiz, Miguel A., et al.
Publicado: (2015)

Retinal and brain damage during multiple sclerosis course: inflammatory activity is a key factor in the first 5 years
por: Pulido-Valdeolivas, Irene, et al.
Publicado: (2020)

Teriflunomide and Epstein–Barr virus in a Spanish multiple sclerosis cohort: in vivo antiviral activity and clinical response
por: Domínguez-Mozo, María Inmaculada, et al.
Publicado: (2023)

Acetate correlates with disability and immune response in multiple sclerosis
por: Pérez-Pérez, Silvia, et al.
Publicado: (2020)

Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-β
por: Bustamante, Marta F., et al.
Publicado: (2015)

Cortical fractal dimension predicts disability worsening in Multiple Sclerosis patients
por: Roura, Eloy, et al.
Publicado: (2021)

Exome sequencing study in patients with multiple sclerosis reveals variants associated with disease course
por: Gil-Varea, Elia, et al.
Publicado: (2018)

Immune tolerance in multiple sclerosis and neuromyelitis optica with peptide-loaded tolerogenic dendritic cells in a phase 1b trial
por: Zubizarreta, Irati, et al.
Publicado: (2019)

Natalizumab-related anaphylactoid reactions in MS patients are associated with HLA class II alleles
por: de la Hera, Belén, et al.
Publicado: (2014)

DRB1*03:01 Haplotypes: Differential Contribution to Multiple Sclerosis Risk and Specific Association with the Presence of Intrathecal IgM Bands
por: de la Concha, Emilio G., et al.
Publicado: (2012)

Increased NLRP3 Inflammasome Activation and Pyroptosis in Patients With Multiple Sclerosis With Fingolimod Treatment Failure
por: Malhotra, Sunny, et al.
Publicado: (2023)

Serum Levels of CXCL13 Are Associated With Teriflunomide Response in Patients With Multiple Sclerosis
por: Fissolo, Nicolás, et al.
Publicado: (2022)

In Vivo Molecular Changes in the Retina of Patients With Multiple Sclerosis
por: Alba-Arbalat, Salut, et al.
Publicado: (2021)

Predictive factors and early biomarkers of response in multiple sclerosis patients treated with natalizumab
por: Dominguez-Mozo, Maria Inmaculada, et al.
Publicado: (2020)

The multiple sclerosis visual pathway cohort: understanding neurodegeneration in MS
por: Martínez-Lapiscina, Elena H, et al.
Publicado: (2014)

Regulatory Lymphocytes Are Key Factors in MHC-Independent Resistance to EAE
por: Marín, Nieves, et al.
Publicado: (2014)

A computational analysis of protein-protein interaction networks in neurodegenerative diseases
por: Goñi, Joaquín, et al.
Publicado: (2008)

Manipulation of Gut Microbiota Influences Immune Responses, Axon Preservation, and Motor Disability in a Model of Progressive Multiple Sclerosis
por: Mestre, Leyre, et al.
Publicado: (2019)

Teriflunomide induces a tolerogenic bias in blood immune cells of MS patients
por: Medina, Silvia, et al.
Publicado: (2019)

Molecular signature associated with cladribine treatment in patients with multiple sclerosis
por: Fissolo, Nicolas, et al.
Publicado: (2023)

Identification of the Immunological Changes Appearing in the CSF During the Early Immunosenescence Process Occurring in Multiple Sclerosis
por: Picón, Carmen, et al.
Publicado: (2021)

Baseline Gene Expression Signatures in Monocytes from Multiple Sclerosis Patients Treated with Interferon-beta
por: Bustamante, Marta F., et al.
Publicado: (2013)

CSF Chitinase 3–Like 2 Is Associated With Long-term Disability Progression in Patients With Progressive Multiple Sclerosis
por: Comabella, Manuel, et al.
Publicado: (2021)

Regional grey matter microstructural changes and volume loss according to disease duration in multiple sclerosis patients
por: Solana, Elisabeth, et al.
Publicado: (2021)

A New Risk Variant for Multiple Sclerosis at 11q23.3 Locus Is Associated with Expansion of CXCR5+ Circulating Regulatory T Cells
por: Gil-Varea, Elia, et al.
Publicado: (2020)

Dynamics and Predictors of Cognitive Impairment along the Disease Course in Multiple Sclerosis
por: Lopez-Soley, Elisabet, et al.
Publicado: (2021)

Anti-Human Herpesvirus 6 A/B Antibodies Titers Correlate With Multiple Sclerosis-Associated Retrovirus Envelope Expression
por: Pérez-Pérez, Silvia, et al.
Publicado: (2021)

Mitochondrial Impairments in Peripheral Blood Mononuclear Cells of Multiple Sclerosis Patients
por: Domínguez-Mozo, María Inmaculada, et al.
Publicado: (2022)

HHV-6 and Multiple Sclerosis
por: Jeanne Billioux, Bridgette, et al.
Publicado: (2014)

Effects of diazoxide in multiple sclerosis: A randomized, double-blind phase 2 clinical trial
por: Villoslada, Pablo, et al.
Publicado: (2015)

Chitinases and chitinase-like proteins as biomarkers in neurologic disorders
por: Pinteac, Rucsanda, et al.
Publicado: (2020)

Genomic Multiple Sclerosis Risk Variants Modulate the Expression of the ANKRD55–IL6ST Gene Region in Immature Dendritic Cells
por: Mena, Jorge, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5orq3el2gmcgpc5bv61jajlhmu