Cargando…

Lung ultrasound for the diagnosis of pneumonia in adults: A meta-analysis

BACKGROUND: Pneumonia is a common and serious infectious disease that can cause high mortality. The role of lung ultrasound (LUS) in the diagnosis of pneumonia is becoming more and more important. METHODS: In the present study, we collected existing evidence regarding the use of LUS to diagnose pneu...

Descripción completa

Detalles Bibliográficos
Autores principales: Long, Ling, Zhao, Hao-Tian, Zhang, Zhi-Yang, Wang, Guang-Ying, Zhao, He-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279077/
https://www.ncbi.nlm.nih.gov/pubmed/28099332
http://dx.doi.org/10.1097/MD.0000000000005713
_version_ 1782502710881288192
author Long, Ling
Zhao, Hao-Tian
Zhang, Zhi-Yang
Wang, Guang-Ying
Zhao, He-Ling
author_facet Long, Ling
Zhao, Hao-Tian
Zhang, Zhi-Yang
Wang, Guang-Ying
Zhao, He-Ling
author_sort Long, Ling
collection PubMed
description BACKGROUND: Pneumonia is a common and serious infectious disease that can cause high mortality. The role of lung ultrasound (LUS) in the diagnosis of pneumonia is becoming more and more important. METHODS: In the present study, we collected existing evidence regarding the use of LUS to diagnose pneumonia in adults and conducted a systematic review to summarize the technique's diagnostic accuracy. We specifically searched the Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, and Embase databases and retrieved outcome data to evaluate the efficacy of LUS for the diagnosis of pneumonia compared with chest radiography or chest computed tomography. The pooled sensitivity (SEN) and specificity (SPE) were determined using the Mantel–Haenszel method, and the pooled diagnostic odds ratio (DOR) was determined using the DerSimonian–Laird method. We also assessed heterogeneity of sensitivity, specificity, and diagnostic odds ratio using the Q and I(2) statistics. RESULTS: Twelve studies containing 1515 subjects were included in our meta-analysis. The SEN and SPE were 0.88 (95% CI: 0.86–0.90) and 0.86 (95% CI: 0.83–0.88), respectively. The pooled negative likelihood ratio (LR) was 0.13 (95% CI: 0.08–0.23), the positive LR was 5.37 (95% CI: 2.76–10.43), and the DOR was 65.46 (95% CI: 29.24–146.56). The summary receiver operating characteristic curve indicated a relationship between sensitivity and specificity. The area under the curve for LUS was 0.95. CONCLUSION: LUS can help to diagnose adult pneumonia with high accuracy.
format Online
Article
Text
id pubmed-5279077
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Wolters Kluwer Health
record_format MEDLINE/PubMed
spelling pubmed-52790772017-02-08 Lung ultrasound for the diagnosis of pneumonia in adults: A meta-analysis Long, Ling Zhao, Hao-Tian Zhang, Zhi-Yang Wang, Guang-Ying Zhao, He-Ling Medicine (Baltimore) 4100 BACKGROUND: Pneumonia is a common and serious infectious disease that can cause high mortality. The role of lung ultrasound (LUS) in the diagnosis of pneumonia is becoming more and more important. METHODS: In the present study, we collected existing evidence regarding the use of LUS to diagnose pneumonia in adults and conducted a systematic review to summarize the technique's diagnostic accuracy. We specifically searched the Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, and Embase databases and retrieved outcome data to evaluate the efficacy of LUS for the diagnosis of pneumonia compared with chest radiography or chest computed tomography. The pooled sensitivity (SEN) and specificity (SPE) were determined using the Mantel–Haenszel method, and the pooled diagnostic odds ratio (DOR) was determined using the DerSimonian–Laird method. We also assessed heterogeneity of sensitivity, specificity, and diagnostic odds ratio using the Q and I(2) statistics. RESULTS: Twelve studies containing 1515 subjects were included in our meta-analysis. The SEN and SPE were 0.88 (95% CI: 0.86–0.90) and 0.86 (95% CI: 0.83–0.88), respectively. The pooled negative likelihood ratio (LR) was 0.13 (95% CI: 0.08–0.23), the positive LR was 5.37 (95% CI: 2.76–10.43), and the DOR was 65.46 (95% CI: 29.24–146.56). The summary receiver operating characteristic curve indicated a relationship between sensitivity and specificity. The area under the curve for LUS was 0.95. CONCLUSION: LUS can help to diagnose adult pneumonia with high accuracy. Wolters Kluwer Health 2017-01-20 /pmc/articles/PMC5279077/ /pubmed/28099332 http://dx.doi.org/10.1097/MD.0000000000005713 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 4100
Long, Ling
Zhao, Hao-Tian
Zhang, Zhi-Yang
Wang, Guang-Ying
Zhao, He-Ling
Lung ultrasound for the diagnosis of pneumonia in adults: A meta-analysis
title Lung ultrasound for the diagnosis of pneumonia in adults: A meta-analysis
title_full Lung ultrasound for the diagnosis of pneumonia in adults: A meta-analysis
title_fullStr Lung ultrasound for the diagnosis of pneumonia in adults: A meta-analysis
title_full_unstemmed Lung ultrasound for the diagnosis of pneumonia in adults: A meta-analysis
title_short Lung ultrasound for the diagnosis of pneumonia in adults: A meta-analysis
title_sort lung ultrasound for the diagnosis of pneumonia in adults: a meta-analysis
topic 4100
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279077/
https://www.ncbi.nlm.nih.gov/pubmed/28099332
http://dx.doi.org/10.1097/MD.0000000000005713
work_keys_str_mv AT longling lungultrasoundforthediagnosisofpneumoniainadultsametaanalysis
AT zhaohaotian lungultrasoundforthediagnosisofpneumoniainadultsametaanalysis
AT zhangzhiyang lungultrasoundforthediagnosisofpneumoniainadultsametaanalysis
AT wangguangying lungultrasoundforthediagnosisofpneumoniainadultsametaanalysis
AT zhaoheling lungultrasoundforthediagnosisofpneumoniainadultsametaanalysis