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A structure-based kinetic model of transcription

During transcription, RNA polymerase moves downstream along the DNA template and maintains a transcription bubble. Several recent structural studies of transcription complexes with a complete transcription bubble provide new insights into how RNAP couples the nucleotide addition reaction to its dire...

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Detalles Bibliográficos
Autores principales: Zuo, Yuhong, Steitz, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279718/
https://www.ncbi.nlm.nih.gov/pubmed/27656764
http://dx.doi.org/10.1080/21541264.2016.1234821
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author Zuo, Yuhong
Steitz, Thomas A.
author_facet Zuo, Yuhong
Steitz, Thomas A.
author_sort Zuo, Yuhong
collection PubMed
description During transcription, RNA polymerase moves downstream along the DNA template and maintains a transcription bubble. Several recent structural studies of transcription complexes with a complete transcription bubble provide new insights into how RNAP couples the nucleotide addition reaction to its directional movement.
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spelling pubmed-52797182017-02-22 A structure-based kinetic model of transcription Zuo, Yuhong Steitz, Thomas A. Transcription Point-of-View During transcription, RNA polymerase moves downstream along the DNA template and maintains a transcription bubble. Several recent structural studies of transcription complexes with a complete transcription bubble provide new insights into how RNAP couples the nucleotide addition reaction to its directional movement. Taylor & Francis 2016-09-22 /pmc/articles/PMC5279718/ /pubmed/27656764 http://dx.doi.org/10.1080/21541264.2016.1234821 Text en © 2017 The Author(s). Published with license by Taylor & Francis http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License http://creativecommons.org/licenses/by-nc/3.0/, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Point-of-View
Zuo, Yuhong
Steitz, Thomas A.
A structure-based kinetic model of transcription
title A structure-based kinetic model of transcription
title_full A structure-based kinetic model of transcription
title_fullStr A structure-based kinetic model of transcription
title_full_unstemmed A structure-based kinetic model of transcription
title_short A structure-based kinetic model of transcription
title_sort structure-based kinetic model of transcription
topic Point-of-View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279718/
https://www.ncbi.nlm.nih.gov/pubmed/27656764
http://dx.doi.org/10.1080/21541264.2016.1234821
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