Cargando…
A structure-based kinetic model of transcription
During transcription, RNA polymerase moves downstream along the DNA template and maintains a transcription bubble. Several recent structural studies of transcription complexes with a complete transcription bubble provide new insights into how RNAP couples the nucleotide addition reaction to its dire...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279718/ https://www.ncbi.nlm.nih.gov/pubmed/27656764 http://dx.doi.org/10.1080/21541264.2016.1234821 |
_version_ | 1782502830129545216 |
---|---|
author | Zuo, Yuhong Steitz, Thomas A. |
author_facet | Zuo, Yuhong Steitz, Thomas A. |
author_sort | Zuo, Yuhong |
collection | PubMed |
description | During transcription, RNA polymerase moves downstream along the DNA template and maintains a transcription bubble. Several recent structural studies of transcription complexes with a complete transcription bubble provide new insights into how RNAP couples the nucleotide addition reaction to its directional movement. |
format | Online Article Text |
id | pubmed-5279718 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-52797182017-02-22 A structure-based kinetic model of transcription Zuo, Yuhong Steitz, Thomas A. Transcription Point-of-View During transcription, RNA polymerase moves downstream along the DNA template and maintains a transcription bubble. Several recent structural studies of transcription complexes with a complete transcription bubble provide new insights into how RNAP couples the nucleotide addition reaction to its directional movement. Taylor & Francis 2016-09-22 /pmc/articles/PMC5279718/ /pubmed/27656764 http://dx.doi.org/10.1080/21541264.2016.1234821 Text en © 2017 The Author(s). Published with license by Taylor & Francis http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License http://creativecommons.org/licenses/by-nc/3.0/, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted. |
spellingShingle | Point-of-View Zuo, Yuhong Steitz, Thomas A. A structure-based kinetic model of transcription |
title | A structure-based kinetic model of transcription |
title_full | A structure-based kinetic model of transcription |
title_fullStr | A structure-based kinetic model of transcription |
title_full_unstemmed | A structure-based kinetic model of transcription |
title_short | A structure-based kinetic model of transcription |
title_sort | structure-based kinetic model of transcription |
topic | Point-of-View |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279718/ https://www.ncbi.nlm.nih.gov/pubmed/27656764 http://dx.doi.org/10.1080/21541264.2016.1234821 |
work_keys_str_mv | AT zuoyuhong astructurebasedkineticmodeloftranscription AT steitzthomasa astructurebasedkineticmodeloftranscription AT zuoyuhong structurebasedkineticmodeloftranscription AT steitzthomasa structurebasedkineticmodeloftranscription |