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The Role of Cysteine Residues in Catalysis of Phosphoenolpyruvate Carboxykinase from Mycobacterium tuberculosis

Mycobacterium tuberculosis (MTb), the causative agent of tuberculosis, can persist in macrophages for decades, maintaining its basic metabolic activities. Phosphoenolpyruvate carboxykinase (Pck; EC 4.1.1.32) is a key player in central carbon metabolism regulation. In replicating MTb, Pck is associat...

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Detalles Bibliográficos
Autores principales:	Machová, Iva, Hubálek, Martin, Lepšík, Martin, Bednárová, Lucie, Pazderková, Markéta, Kopecký, Vladimír, Snášel, Jan, Dostál, Jiří, Pichová, Iva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279734/ https://www.ncbi.nlm.nih.gov/pubmed/28135343 http://dx.doi.org/10.1371/journal.pone.0170373

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