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Programmable Genome Editing Tools and their Regulation for Efficient Genome Engineering
Targeted genome editing has become a powerful genetic tool for studying gene function or for modifying genomes by correcting defective genes or introducing genes. A variety of reagents have been developed in recent years that can generate targeted double-stranded DNA cuts which can be repaired by th...
Autores principales: | Guha, Tuhin Kumar, Wai, Alvan, Hausner, Georg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279741/ https://www.ncbi.nlm.nih.gov/pubmed/28179977 http://dx.doi.org/10.1016/j.csbj.2016.12.006 |
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