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Mesenchymal Cell Reprogramming in Experimental MPL(W515L) Mouse Model of Myelofibrosis
Myelofibrosis is an indicator of poor prognosis in myeloproliferative neoplasms (MPNs), but the precise mechanism(s) contributing to extracellular matrix remodeling and collagen deposition in the bone marrow (BM) niche remains unanswered. In this study, we isolated mesenchymal stromal cells (MSCs) f...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279751/ https://www.ncbi.nlm.nih.gov/pubmed/28135282 http://dx.doi.org/10.1371/journal.pone.0166014 |