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Mesenchymal Cell Reprogramming in Experimental MPL(W515L) Mouse Model of Myelofibrosis

Myelofibrosis is an indicator of poor prognosis in myeloproliferative neoplasms (MPNs), but the precise mechanism(s) contributing to extracellular matrix remodeling and collagen deposition in the bone marrow (BM) niche remains unanswered. In this study, we isolated mesenchymal stromal cells (MSCs) f...

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Detalles Bibliográficos
Autores principales:	Han, Ying, Yue, Lanzhu, Wei, Max, Ren, Xiubao, Shao, Zonghong, Zhang, Ling, Levine, Ross L., Epling-Burnette, Pearlie K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279751/ https://www.ncbi.nlm.nih.gov/pubmed/28135282 http://dx.doi.org/10.1371/journal.pone.0166014

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