Congenital Cataract in Gpr161(vl/vl) Mice Is Modified by Proximal Chromosome 15

The morphology and severity of human congenital cataract varies even among individuals with the same mutation, suggesting that genetic background modifies phenotypic penetrance. The spontaneous mouse mutant, vacuolated lens (vl), arose on the C3H/HeSnJ background. The mutation disrupts secondary len...

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Detalles Bibliográficos
Autores principales: Li, Bo I., Ababon, Myka R., Matteson, Paul G., Lin, Yong, Nanda, Vikas, Millonig, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279759/
https://www.ncbi.nlm.nih.gov/pubmed/28135291
http://dx.doi.org/10.1371/journal.pone.0170724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279759/
https://www.ncbi.nlm.nih.gov/pubmed/28135291
http://dx.doi.org/10.1371/journal.pone.0170724

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