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Congenital Cataract in Gpr161(vl/vl) Mice Is Modified by Proximal Chromosome 15
The morphology and severity of human congenital cataract varies even among individuals with the same mutation, suggesting that genetic background modifies phenotypic penetrance. The spontaneous mouse mutant, vacuolated lens (vl), arose on the C3H/HeSnJ background. The mutation disrupts secondary len...
Autores principales: | Li, Bo I., Ababon, Myka R., Matteson, Paul G., Lin, Yong, Nanda, Vikas, Millonig, James H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279759/ https://www.ncbi.nlm.nih.gov/pubmed/28135291 http://dx.doi.org/10.1371/journal.pone.0170724 |
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