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Structure and Synaptic Function of Metal Binding to the Amyloid Precursor Protein and its Proteolytic Fragments

Alzheimer’s disease (AD) is ultimately linked to the amyloid precursor protein (APP). However, current research reveals an important synaptic function of APP and APP-like proteins (APLP1 and 2). In this context various neurotrophic and neuroprotective functions have been reported for the APP proteol...

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Detalles Bibliográficos
Autores principales:	Wild, Klemens, August, Alexander, Pietrzik, Claus U., Kins, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5281630/ https://www.ncbi.nlm.nih.gov/pubmed/28197076 http://dx.doi.org/10.3389/fnmol.2017.00021

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