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Chemosensitivity of U251 Cells to the Co-treatment of D-Penicillamine and Copper: Possible Implications on Wilson Disease Patients
D-Penicillamine (PA), a copper chelator, and one of the recommended drugs for treatment of Wilson disease (WD) has been reported to worsen the symptoms of patients with neurologic presentations. However, the cause of this paradoxical response has not been fully elucidated and requires further invest...
Autores principales: | Katerji, Meghri, Barada, Kassem, Jomaa, Mustapha, Kobeissy, Firas, Makkawi, Ahmad-Kareem, Abou-Kheir, Wassim, Usta, Julnar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5281637/ https://www.ncbi.nlm.nih.gov/pubmed/28197071 http://dx.doi.org/10.3389/fnmol.2017.00010 |
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