Hydralazine Induced Lupus Syndrome Presenting with Recurrent Pericardial Effusion and a Negative Antinuclear Antibody

Drug induced lupus erythematosus (DIL or DILE) is an autoimmune disorder caused by chronic use of certain drugs. We report a unique case of hydralazine induced lupus syndrome (HILS) with a negative antinuclear antibody in a female patient who was on hydralazine for a period of 1.5–2 years and develo...

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Autores principales: Iyer, Praneet, Dirweesh, Ahmed, Zijoo, Ritika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282409/
https://www.ncbi.nlm.nih.gov/pubmed/28194293
http://dx.doi.org/10.1155/2017/5245904
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author Iyer, Praneet
Dirweesh, Ahmed
Zijoo, Ritika
author_facet Iyer, Praneet
Dirweesh, Ahmed
Zijoo, Ritika
author_sort Iyer, Praneet
collection PubMed
description Drug induced lupus erythematosus (DIL or DILE) is an autoimmune disorder caused by chronic use of certain drugs. We report a unique case of hydralazine induced lupus syndrome (HILS) with a negative antinuclear antibody in a female patient who was on hydralazine for a period of 1.5–2 years and developed recurrent pericardial effusion as a result of it. Initially her condition was managed with a pericardial window. The recurrence of a massive pericardial effusion necessitated a right hemipericardiectomy. After hydralazine was stopped, she never had any further episodes of pericardial effusion or tamponade.
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spelling pubmed-52824092017-02-13 Hydralazine Induced Lupus Syndrome Presenting with Recurrent Pericardial Effusion and a Negative Antinuclear Antibody Iyer, Praneet Dirweesh, Ahmed Zijoo, Ritika Case Rep Rheumatol Case Report Drug induced lupus erythematosus (DIL or DILE) is an autoimmune disorder caused by chronic use of certain drugs. We report a unique case of hydralazine induced lupus syndrome (HILS) with a negative antinuclear antibody in a female patient who was on hydralazine for a period of 1.5–2 years and developed recurrent pericardial effusion as a result of it. Initially her condition was managed with a pericardial window. The recurrence of a massive pericardial effusion necessitated a right hemipericardiectomy. After hydralazine was stopped, she never had any further episodes of pericardial effusion or tamponade. Hindawi Publishing Corporation 2017 2017-01-17 /pmc/articles/PMC5282409/ /pubmed/28194293 http://dx.doi.org/10.1155/2017/5245904 Text en Copyright © 2017 Praneet Iyer et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Iyer, Praneet
Dirweesh, Ahmed
Zijoo, Ritika
Hydralazine Induced Lupus Syndrome Presenting with Recurrent Pericardial Effusion and a Negative Antinuclear Antibody
title Hydralazine Induced Lupus Syndrome Presenting with Recurrent Pericardial Effusion and a Negative Antinuclear Antibody
title_full Hydralazine Induced Lupus Syndrome Presenting with Recurrent Pericardial Effusion and a Negative Antinuclear Antibody
title_fullStr Hydralazine Induced Lupus Syndrome Presenting with Recurrent Pericardial Effusion and a Negative Antinuclear Antibody
title_full_unstemmed Hydralazine Induced Lupus Syndrome Presenting with Recurrent Pericardial Effusion and a Negative Antinuclear Antibody
title_short Hydralazine Induced Lupus Syndrome Presenting with Recurrent Pericardial Effusion and a Negative Antinuclear Antibody
title_sort hydralazine induced lupus syndrome presenting with recurrent pericardial effusion and a negative antinuclear antibody
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282409/
https://www.ncbi.nlm.nih.gov/pubmed/28194293
http://dx.doi.org/10.1155/2017/5245904
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AT zijooritika hydralazineinducedlupussyndromepresentingwithrecurrentpericardialeffusionandanegativeantinuclearantibody

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