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Unintended targeting of Dmp1-Cre reveals a critical role for Bmpr1a signaling in the gastrointestinal mesenchyme of adult mice

Cre/loxP technology has been widely used to study cell type-specific functions of genes. Proper interpretation of such data critically depends on a clear understanding of the tissue specificity of Cre expression. The Dmp1-Cre mouse, expressing Cre from a 14-kb DNA fragment of the mouse Dmp1 gene, ha...

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Detalles Bibliográficos
Autores principales: Lim, Joohyun, Burclaff, Joseph, He, Guangxu, Mills, Jason C, Long, Fanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282469/
https://www.ncbi.nlm.nih.gov/pubmed/28163952
http://dx.doi.org/10.1038/boneres.2016.49

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