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Histone H4 expression is cooperatively maintained by IKKβ and Akt1 which attenuates cisplatin-induced apoptosis through the DNA-PK/RIP1/IAPs signaling cascade

While chromatin remodeling mediated by post-translational modification of histone is extensively studied in carcinogenesis and cancer cell’s response to chemotherapy and radiotherapy, little is known about the role of histone expression in chemoresistance. Here we report a novel chemoresistance mech...

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Detalles Bibliográficos
Autores principales:	Wang, Ruixue, Zheng, Xuelian, Zhang, Lei, Zhou, Bin, Hu, Huaizhong, Li, Zhiping, Zhang, Lin, Lin, Yong, Wang, Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282510/ https://www.ncbi.nlm.nih.gov/pubmed/28139737 http://dx.doi.org/10.1038/srep41715

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